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+ Become a sponsorNomination created on December 4, 2025
Enthusiast open-source dev & data scientist, PhD student in neuroscience @Neurospin_91 @Parietal_inria
Deeply researched interviews www.dwarkesh.com
Alexis Thual is building Karavela’s foundation model of the brain, fresh off a €2M+ pre-seed to assemble a massive task-based fMRI dataset for new biomarkers and brain–computer interfaces. He is targeting 10,000+ hours of brain activity from 1,000+ participants with partners like NeuroSpin and the Paris Brain Institute, exactly the scale recent fMRI–language foundation models suggest is now useful.
UNESCO just adopted the first global ethical standards for neurotechnology in November 2025, and the policy fight over how neural data is governed is heating up in 2026. This is the moment to hear a founder who can explain how to build powerful brain decoders while protecting mental privacy.
Dwarkesh’s audience cares about frontier AI that actually ships into clinics, and Alexis is moving from prototype to clinical collaborations right now. Put him in the hot seat to clarify timelines, dataset sharing, and safeguards.
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