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Industry veterans, degenerate gamblers & besties Chamath Palihapitiya, Jason Calacanis, David Sacks & David Friedberg cover all things economic, tech, political, social & poker.
$10 pledged across 1 nomination on this show.
AI Cyber Panic, Ken Griffin's Bubble Warning, The Fall of France?
with Guest
(0:00) Bestie intros! (0:11) Ken Griffin's AI bubble warning (8:19) Palo Alto Networks CEO Nikesh Arora joins (14:24) AI Cyber panic: PHP exploits and the tumultuous year ahead (44:17) France on the brink: Riots, immigration referendum, debt crisis (1:31:49) Trump's second half strategy, Press Secre
Arvind Krishna & Nikesh Arora: Quantum Threat, Open vs Frontier AI, AI Cyber Warfare & SaaS Collapse
with Guest
(0:00) Arvind Krishna & Nikesh Arora talk about Quantum Computing's Threat to Encryption (9:07) Open Weight vs. Frontier AI Models (18:07) AI and Cyber Warfare (21:14) AI Regulation and the Global AI Arms Race (30:32) Vertical Integration and Software Consolidation Follow Nikesh: https://x.com/nik
Dylan Field: Is AI Replacing Designers?, Design is the New Code & Democratizing Creativity
with Guest
(0:00) Dylan Field joins the show: Figma's origin story and mission (3:16) Adobe's $20B deal blocked: inside the antitrust fight (12:29) Is AI killing SaaS? Frontier Companies vs. Figma, the "SaaS apocalypse" (18:52) Creativity in the AI era: why taste and boldness win (36:02) Human agency, AI's pro
CoreWeave Crash, AI Trade Cracks, Anthropic IPO Red Flags, Bill Gates Doomer
with Guest
(0:00) Ben Horowitz fills in for Friedberg! (2:18) CoreWeave's debt selloff: did the AI bubble just pop? (31:14) AI's deflationary impact: decompiled software (45:44) Anthropic's investor day gets mixed reactions (1:03:45) Psyop Corner: Anthropic warns about self-replicating models on IoT devices (1
Elizabeth Holmes' Husband Billy Evans: The Trial, Prison & Nathan Fielder's Documentary
with Guest
(0:00) Billy Evans joins Friedberg (3:38) How they met, Elizabeth the person vs the headlines, indictment (11:02) Life on trial, having a child, where she went wrong in fundraising (19:28) Understanding the verdict, sentencing, and the mistake of staying silent (26:09) Elizabeth calls from prison, h
Martin Shkreli: Big Pharma's Blind Spot, Betting Against Quantum & What Prison Taught Him
with Guest
(0:00) Martin Shkreli joins the Besties! (0:55) Why quantum computing is a one-trick business and why he's betting against it (7:42) The drugs big pharma sells too cheap and his journey from hedge fund trader to pharma (11:37) AI, drug discovery, and who actually wins (21:32) Brilliance and rule-bre
The Frontrunners
Competing to be All-In with Chamath, Jason, Sacks & Friedberg's next guest
| # | Nominee | Tags | Votes | Recent Voters | |
|---|---|---|---|---|---|
| 1 | DA  Dario Amodei @darioamodei | Debug Tag+1 | 29$10 Pledged$196 Boosted | ||
| 2 | ZK  Zohran Kwame Mamdani @zohrankmamdani | NYC Mayoral Race+2 | 4 | ||
| 3 | B  Balaji @balajis | Network State+2 | 2 | ||
| 4 | MZ  Mark Zuckerberg @finkd | — | 1 | ||
| 5 | SG  Scott Galloway @profgalloway | — | 1 | ||
| 6 | JV  JD Vance @jdvance | Populist Economics+2 | 1 | ||
| 7 | RP  Ron Paul @ronpaul | Federal Reserve+2 | 1 | ||
| 8 | BA  Bill Ackman @billackman | — | 1 | ||
| 9 | LH  Lawrence H. Summers @lhsummers | Inflation and Fed Policy+2 | 1 | ||
| 10 | SN  Satya Nadella @satyanadella | OpenAI Partnership+2 | 1 | ||
| 11 | MA  Marc Andreessen 🇺🇸 @pmarca | AI Policy+2 | 1 | ||
| 12 | AR  Andrew Ross Sorkin @andrewrsorkin | — | 1 |
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